A one-pot amidation of primary nitroalkanes.
نویسندگان
چکیده
It has been over a half-century since Kornblum demonstrated the conversion of a primary nitroalkane to a carboxylic acid; addition of an amine results in carboxylic acid formation as well. We describe the formation of amides from terminal nitroalkanes in a two-step, one-pot reaction involving tandem halogenation/umpolung amide synthesis (UmAS).
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ورودعنوان ژورنال:
- Chemical communications
دوره 52 1 شماره
صفحات -
تاریخ انتشار 2016